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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRAP1
All Species:
42.73
Human Site:
S2165
Identified Species:
94
UniProt:
P42345
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42345
NP_004949.1
2549
288892
S2165
P
S
L
Q
V
I
T
S
K
Q
R
P
R
K
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535407
2550
288910
S2166
P
S
L
Q
V
I
T
S
K
Q
R
P
R
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLN9
2549
288718
S2165
P
S
L
Q
V
I
T
S
K
Q
R
P
R
K
L
Rat
Rattus norvegicus
P42346
2549
288776
S2165
P
S
L
Q
V
I
T
S
K
Q
R
P
R
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510680
2493
282092
S2109
P
S
L
Q
V
I
T
S
K
Q
R
P
R
K
L
Chicken
Gallus gallus
XP_417614
2463
280042
S2083
P
S
L
Q
V
I
T
S
K
Q
R
P
R
K
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001070679
2515
286136
S2131
P
S
L
Q
V
I
T
S
K
Q
R
P
R
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VK45
2470
281015
S2086
T
N
L
Q
V
I
T
S
K
Q
R
P
R
K
L
Honey Bee
Apis mellifera
XP_625130
2442
278856
S2064
S
S
M
Q
V
I
T
S
K
Q
R
P
R
K
L
Nematode Worm
Caenorhab. elegans
Q95Q95
2697
306510
S2341
S
K
M
N
V
I
T
S
K
Q
R
P
R
K
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32600
2474
281549
S2106
P
V
F
S
V
I
S
S
K
Q
R
P
R
K
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
99.4
N.A.
98.9
98.9
N.A.
88.8
93.7
N.A.
89.8
N.A.
54
62
34.7
N.A.
Protein Similarity:
100
N.A.
N.A.
99.5
N.A.
99.2
99.2
N.A.
91.2
95.4
N.A.
94.5
N.A.
69.8
75.7
53.4
N.A.
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
100
100
N.A.
100
N.A.
86.6
86.6
66.6
N.A.
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
100
100
N.A.
100
N.A.
93.3
93.3
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
40.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
58.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
0
0
0
100
0
0
0
0
100
0
% K
% Leu:
0
0
73
0
0
0
0
0
0
0
0
0
0
0
82
% L
% Met:
0
0
19
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
73
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% P
% Gln:
0
0
0
82
0
0
0
0
0
100
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
100
0
100
0
0
% R
% Ser:
19
73
0
10
0
0
10
100
0
0
0
0
0
0
0
% S
% Thr:
10
0
0
0
0
0
91
0
0
0
0
0
0
0
0
% T
% Val:
0
10
0
0
100
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _